Grants, awards & surveys

Updates on research grants, awards and surveys published by the 3RCC.

Katrin Wendrich and Tijmen Booij win 3RCC Poster Award at LS2

Tijmen Booij, ETH Zurich; Katrin Wendrich, University of Fribourg

The winners of the 3RCC Poster Award are Tijmen Booij from Nexus Personalized Health Technologies at the ETH Zurich for his replacement project, and Katrin Wendrich from the Department of Biology and Biochemistry at the University of Fribourg for refinement.

Booij and colleagues developed a screening platform to test thousands of drugs simultaneously using pancreatic cancer organoids. They propagated pancreatic cancer PDX/organoid lines in 3D extracellular matrix and expanded for screening in more physiologically relevant in vitro assays with the aim to select more patient-relevant therapies. Booij expects these techniques to result in a reduction of the number of animal studies required for drug evaluation, as researchers may identify less beneficial drugs already in vitro.

Wendrich and colleagues investigated the influence of the circadian clock on sleep and brain metabolism. They in particular studied how the systemic circadian clock as well as the astrocytic and neuronal clocks modulate sleep architecture and glymphatic clearance under both physiological and sleep deprivation (SD) conditions. Wendrich used the non-invasive PiezoSleep system for sleep recordings, enrichment of the environment and gentle handling methods as refinement approaches, and to keep confounding stress as low as possible.  

Call for nominations for the Swiss 3RCC 3Rs award

The 3RCC offers an award of CHF 5,000 to scientists who have significantly contributed to the advancement of Replacement, Reduction, Refinement of animal experimentation (the principle of 3Rs) in the area of life sciences. The applications will be evaluated based on the quality of the contributions and on their impact on the advancement of the principle of the 3Rs in either a scientific, regulatory, industrial or educational context. The application deadline is 17 June 2019.
More info: https://swiss3rcc.org/2019/01/01/442/

First 3RCC call for 3Rs research projects closed

The 3RCC closed its first call for projects on 21 January. We received 54 applications from 12 different institutions. About half of the projects focus on replacement, while 30% deal with reduction and 20% with refinement. We thank all applicants for their submissions. Our reviewers will now assess the proposals. The funding programme with an indicative overall budget of CHF 1,200,000 will subsidize at least one high-impact project in each of the 3Rs. More info: https://swiss3rcc.org/category/research-funding