Advancing the 3Rs beyond minimum compliance to support organisational change and strengthen responsible research

The Swiss 3RCC has partnered with the University of Applied Sciences and Arts Northwestern Switzerland to offer a unique Certificate of Advanced Studies (CAS) programme focused on how the principle of Replacement, Reduction and Refinement (3Rs) can be strategically implemented within research organisations. The programme explores the evolving landscape of scientific methods, including new strategies for reduction and refinement as well as replacement approaches such as New Approach Methodologies (NAMs), and examines how these innovations can be integrated into research and testing practice.

Aims and benefits

Researchers and institutional stakeholders increasingly face complex questions when applying the 3Rs in practice. Beyond the scientific foundations, the CAS addresses the regulatory, organ-isational and institutional contexts that shape 3Rs adoption. The programme equips participants with the knowledge and analytical tools to navigate implementation challenges – such as decision-making processes, governance structures and barriers to adoption – and to advance the 3Rs beyond minimum compliance, using them as a comprehensive framework for guiding good and responsible research practice within research organisations.

Target audience

This part-time programme is designed for professionals who operate at the interface of regulation, science and institutional practice who are seeking practical ways to advance 3Rs implementation beyond minimum compliance and integrate them more strategically within their organisations.

It is particularly suited for professionals involved in animal experimentation and its governance in research institutions, universities, regulatory bodies and public authorities, as well as in the pharmaceutical, biotechnology, chemical and consumer goods industries.

The programme is especially relevant for:

• Heads and managers of animal facilities


• 3Rs officers, animal welfare officers and designated veterinarians


• Members of cantonal animal experimentation committees and veterinary authorities


• Preclinical and translational researchers


• Study directors, principal investigators and senior scientists


• Research strategy, governance and compliance professionals


• Regulatory affairs professionals