Project Objectives Develop mathematical algorithms that optimise breeding strategies for genetically modified laboratory animals, reducing the number of surplus animals produced. Create a user-friendly online tool (Multigeneration Breeding Planner) that enables...
BACKGROUND The home lab (Rubin Lab, DBMR; University of Bern) focuses on in vitro models to investigate lineage plasticity and metastasis and has most recently developed a novel organoid-based model to examine tumour-host interactions and the metastatic...
BACKGROUND Our lab develops organs-on-chip (OOC) models, focusing on the lungs, liver and gut. We are creating vascularized tissues-on-chip (patent filed) that better mimic the tissue microenvironment, enabling interaction studies between the vascular systems and...
BACKGROUND At my home lab I developed an air-liquid-interface in-vitro model of the red fox (Vulpes vulpes) respiratory tract to study host-parasite interactions in canids. This model is crucial for understanding the pathogenesis and immune responses in canid lungworm...
BACKGROUND The Centre of Experimental Rheumatology specializes in the investigation of rheumatic and skeletal disorders, including systemic sclerosis (SSc). SSc is a paradigm fibrotic disease characterized by multi-organ fibrosis, including the skin. Currently, tools...
Project Objectives Develop an integrated hardware–software platform for automated welfare assessment. Combine 3D gait analysis, grimace scoring and behavioural motif analysis. Generate robust training datasets across multiple collaborating laboratories. Benchmark...
