Application of non-surgical embryo transfer for the generation of transgenic models

Keywords: Non surgical embryo transfer; Generation of transgenic models
Budget: CHF 20'000.-

Aim

• Proposal for a more humane procedure for generating transgenic mouse and rat models

• Current method involves invasive surgery, anesthesia, and potential post-operative pain

• Suggests implementing non-surgical embryo transfer (NSET) for mice and rats, similar to human procedures

• Aims to compare NSET with conventional embryo transfer and potentially replace invasive methods to reduce animal suffering and complications