Researchers in Switzerland and beyond are continuously advancing both science and the 3Rs principle. With these advancements come new techniques, guidelines for working with animals and non-animal models, and policy briefs that bridge science and policy. Here, you’ll find practical resources to support your work—whether you’re conducting research, ensuring animal welfare, or shaping policy.
POLICY BRIEFS
GUIDELINES & RESOURCES
EXTERNAL RESOURCES
Policy Brief
Policy Brief
Gentle Handling Report 2025
In 2020 and 2024, the Swiss 3RCC and the Swiss Culture of Care Network carried out two surveys on the use of non-aversive mouse handling methods among animal care and research staff in Switzerland. Here are the results from the surveys.
3RCC GUIDELINES AND RESOURCES
3RCC GUIDELINES AND RESOURCES


Tech3Rs newsletter for animal care staff
Regular newsletter produced by the NC3Rs and translated in national languages providing animal caretakers and technicians with recent advances in the 3Rs.


Using 3D printed mouse tail for IV injection training
Dr. Felix Gantenbein takes us through using a 3D printed tail to practice IV injections for mice.


Inside the lab: standardised methods for a human in vitro Blood-Brain Barrier model
Transparent, standardised methods are essential for advancing human-relevant research and the 3Rs....
External resources
External resources
Recombinant antibodies database
FC3R Project: The FC3R aims to replace the use of antibodies of animal origin, which present both ethical and scientific robustness problems (variability, lack of reproducibility, etc.). In partnership with the Association Française d'Histotechnologie (AFH) and...
Basement membrane extracts / Matrigel alternatives database
The BME-free Database is part of the 3Rs Research Tools Program managed and hosted by the 3Rs Centre Utrecht, and is dedicated at facilitating researchers to replace, reduce and refine animal experiments. When mentioning the BME-free Database, please cite its...
FCS-free (Fetal Calf Serum) database
The FCS-free Database is part of the 3Rs Research Tools Program managed and hosted by the 3Rs Centre Utrecht, and are dedicated at facilitating researchers to replace, reduce and refine animal experiments. When mentioning the FCS-free Database, please also use its...
RE-place (NAMs)
New and innovative technologies continue to be developed across the life sciences. In recent years computer modelling, artificial intelligence, sophisticated cell cultures, organ-on-a-chip and many more technologies have tremendously advanced. These technologies are...
NAT (Non-Animal Technologies)
The NAT database (Non-Animal Technologies) contains information on modern non-animal technologies from various areas of biomedicine and life sciences, based on scientific studies and publications.
SMAFIRA (literature search on alternatives)
The SMAFIRA project aims to develop a search engine for supporting the retrieval of alternative methods to animal experiments. This project was initiated by the German Federal Institute for Risk Assessment (BfR) which performs the function of the “German Centre for...
Cancer-SOLES (preclinical cancer research)
Cancer-SOLES is a new digital platform for the systematic and continuous preparation of preclinical evidence in preclinical cancer research, with a special focus on small molecule targeting therapies. Cancer-SOLES (Systematic Online Living Evidence Summary) was...
3Rs Info Hub
The 3Rs InfoHub guides you toward the best approaches intended to replace, reduce or refine animal testing. Test your knowledge with 3R Quizzes and learn about 3Rs research on individual organs!
Cellosaurus (cell lines)
The Cellosaurus (https://www.cellosaurus.org/) is a knowledge resource on cell lines. It attempts to describe all cell lines used in biomedical research. Its scope includes: Immortalized cell lines Naturally immortal cell lines (example: stem cell lines) Finite life...
Forum on behavioral research in laboratory animals
www.TheBehaviourForum.org is an online forum for discussion of animal behaviour experiments. TheBehaviourForum was developed as part of the collaborative EU COST Action grant which is focused on automated home cage monitoring (TEATIME; www.cost-teatime.org/). However,...
